Assessment of 11 patient-derived melanoma cell lines showed that, while significantly lower compared to a prostate cancer cell line (LNCaP), 4 of the 11 cell lines (WM793, WM1366, IPC298, and A375) express detectable AR protein, regardless of mutation background or sex origin (Fig. 1c and Supplementary Fig. 1a). This evidence concerns the gene AR and prostate cancer.