PTPN18 and Alzheimer disease: In the hippocampus of male APP/PS1 AD mice, exclusive upregulation was observed in 18 gene candidates, i.e., Sgk1, Ncf1, Adamtsl4, Hck, St8sia6, Gm20743, Irf9, Pfkfb3, B2m, Arrdc2, Cebpa, Synpo2, Cep126, Rhoh, Hist1h2be, Clec5a, Cd86, Ptpn18.