In the RS cortex of female APP/PS1 AD mice, 25 candidates exhibited signature character, i.e., Gusb, Slc14a1, Mir142hg, Cyth4, Gpr34, Plek, Ccl9, Aif1, Psmb9, Lair1, Hk3, Csf2rb, Tlr12, Adora3, Apbb1ip, Pycard, Vav1, Oas1a, Ifi27l2a, Hexb, Ncf4, Fcrls, Irf5, Havcr2, Mlxipl. This evidence concerns the gene MIR142HG and Alzheimer disease.