NPPB and COVID-19: NT-proBNP levels were also significantly higher at 3-months post-COVID-19 compared to healthy controls (415 ± 640.3 vs. 127 ± 65.0, P < 0.01) and remained elevated up to 6-months (442 ± 670 vs. 127 ± 65.0, P < 0.05) and 12 months after infection (222 ± 176 vs. 127 ± 65.0, P < 0.05) (Fig. 1F; Table 3).