In contrast, we observe more Brd4 binding near Nkx2-1 (also known as TTF1) and higher expression of this gene in male GBM cells, Nkx2-1 has been reported to promote metastasis and its expression is associated with a molecular subtype of IDH-wildtype GBM (Prok and Prayson 2006, Wildeboer et al. 2006, Han et al. 2021, Suwala et al. 2021), which has a poor prognosis. Here, BRD4 is linked to glioblastoma.