Our reanalysis of published data generated several novel hypotheses, such as the role of Nfia and Zbtb20 binding at the Pou3f2 enhancer in astrocytogenesis, novel binding of Tye7p upon gcr2 knockout, and novel TF families that may be involved in sex difference in GBM that were not identified in the original publications (see Supplementary Notes and Supplementary Table S6). Here, POU3F2 is linked to glioblastoma.