After PSM, in 56 960 patients with stroke with multimorbidity for each group, the higher risk of composite outcome (HR, 1.47 [95% CI, 1.44–1.50]), all-cause death (HR, 2.64 [95% CI, 2.54–2.73]), heart failure (HR, 1.33 [95% CI, 1.29–1.37]), atrial fibrillation (HR, 1.11 [95% CI, 1.09–1.14]), severe ventricular arrhythmias (HR, 1.51 [95% CI, 1.38–1.66]), myocardial infarction (HR, 1.60 [95% CI, 1.52–1.69]), and Takotsubo cardiomyopathy (HR, 1.64 [95% CI, 1.33–2.03]) in patients with reduced albumin levels was consistent with the main analysis (Table S3). This evidence concerns the gene ALB and stroke disorder.