Consistent with the main analysis, patients with reduced albumin levels showed a higher risk of heart failure (HR, 1.81 [95% CI, 1.72–1.91]), atrial fibrillation (HR, 1.48 [95% CI, 1.40–1.55]), severe ventricular arrhythmias (HR, 1.52 [95% CI, 1.39–1.67]), myocardial infarction (HR, 2.22 [95% CI, 1.98–2.49]), and Takotsubo cardiomyopathy (HR, 2.14 [95% CI, 1.56–2.93]) compared to patients with normal albumin levels (Table 2). This evidence concerns the gene ALB and heart failure.