MAPT and Alzheimer disease: Moreover, we also found increased Tau phosphorylation in AD-ROs compared to CTR-ROs using antibodies against two different phosphorylated forms of Tau: AT8 (phosphorylation in Ser202, Thr205; Figures 3a–c, g–i), and T231 (phosphorylation in Thr231; Figures 3d–f, j–l).