Using the 108 markers as well as PKM2 and myostatin (MSTN), in batch 1 and 2 cohorts, we found 31 markers with false discovery rate (FDR) p values < 0.10 from univariable Kruskal-Wallis tests for the associations of markers with HCC vs. cirrhosis, which we retained for further analysis (Table 2). Here, PKM is linked to Cirrhosis.