IL1R1 and colitis: IL-1β induces innate pathology in Helicobacter hepaticus-associated intestinal inflammation by increasing the recruitment of granulocytes & ILCs’ accumulation & stimulationT cell transfer colitis model ➔ critical role for T cell-specific IL-1R signals in the accumulation & survival of pathogenic Th cells in the colonIL-1β induces Th17 responses from Th cells & ILCs in the intestineIL-1β & IL-23 ➔ interaction to maintain intestinal innate & adaptive inflammatory responses