To induce VAs in a Brugada-like model (Scn5a+/−) and in a model of arrhythmogenic cardiomyopathy (LmnaH222P/H222P), we chose to apply progressive protocols with the aim to assess the susceptibility of these models to PES-triggered arrhythmias by comparison with WT mice. The gene discussed is SCN5A; the disease is cardiac arrhythmia.