PAX6 and muscular dystrophy-dystroglycanopathy, type A: Primary microphthalmia has been related to genetic mutations (SOX2, PAX6, OTX2, RAX, CHX10, FOXE3, and CRYBA4), chromosomal mutations (trisomy 13 and trisomy 18) [7, 10, 11, 21, 27, 34], and many syndromes such as CHARGE syndrome, Walker–Warburg syndrome, Dandy–Walker syndrome, Goldenhar syndrome, Lowe syndrome, and Fraser syndrome [10, 11].