The number of tumor‐infiltrating immune cells outside the TLSs located at the tumor margin was greater than that at the tumor centre, and the main tumor‐infiltrating immune cells were CD4+ T cells, CD8+ T cells, CD20+ B cells, CD45RO+ memory T cells, CD11c+ DCs, NCR1+ NK cells, FOXP3+ Tregs and CD15+ TANs (Figure 3b). Here, CD4 is linked to neoplasm.