AFP and neoplasm: Three independent factors affected PFS: tumor size (HR: 1.110; 95% CI: 1.037-1.188; P = 0.003), AFP (HR: 1.940; 95% CI: 1.095-3.437; P = 0.023) and PLR (HR: 3.540; 95% CI: 2.004-6.254; P = 0.000).