In the subgroups with low PD-L1 expression (a total of 29.8% of all patients analysed), median OS was 8.7 months (95% CI 7.7-12.4) and 10.2 months (9.3-11.7) for squamous and non-squamous histologies, respectively, and 10.2 and 11.8 months for patients with tumours showing 1-49% PD-L1 expression. Here, CD274 is linked to neoplasm.