GSEA analysis showed that there were 22 gene sets in the collections h.all.v7.4.symbols (Hallmarks) that were upregulated in orbital MALT lymphoma (FDR q-value<0.05), including epithelial-mesenchymal transition (EMT), inflammatory response, and IL6-JAK-STAT3 signaling, in addition to 29 gene sets when the FDR q-value was <0.25 (Figure 2A). Here, IL6 is linked to MALT lymphoma.