In ocular MALT lymphoma, chromosomal abnormalities are associated with MALT lymphoma: trisomy 3, 7, 12, and 18, somatic deletion and/or mutation of A20, and the chromosomal translocations are especially found in patients with ocular MALT, and that genetic translocations affect or target different regulating genes, thereby leading to the formation or upregulation of proteins that ultimately activate NF-κB (27). The gene discussed is NFKB1; the disease is MALT lymphoma.