To gain insight into the role of the five statistically up-regulated proteins (LCP1, PRDX2, TAGLN2, LUM, OGN), in IPF patients at Stage II and/or with impaired lung function, we explored their known and predicted molecular interactors using the bioinformatic software STRING v11.5 (40). This evidence concerns the gene TAGLN2 and idiopathic pulmonary fibrosis.