The potential of B7-H3-SDIE to induce target cell lysis was additionally confirmed by analyzing tumor cell lysis over a 120-hour period using xCELLigence assays, despite the varying morphological features, growth rates, and levels of B7-H3 surface expression across the different pancreatic cancer cell lines (Figure 4C). This evidence concerns the gene CD276 and familial pancreatic carcinoma.