For instance, dazl, involved in differentiation of germ cells (Yu et al., 2009); cldn10, an ovarian cancer biomarker in the chicken (Seo et al., 2010); and asz1, associated with gametogenesis and piRNA metabolism (Yi et al., 2014; Wang et al., 2017). The gene discussed is CLDN10; the disease is ovarian carcinoma.