CXCL12 and neoplasm: Interestingly, Wang et al. observed that a population of CD62Ldim expressing neutrophils were recruited in the lungs of 4T1 tumor-bearing mice, which was owing to that CXCL12 secreted from the lungs had propensity to bind to CXCR4 on the CD62Ldim expressing neutrophils to enable them to migrate to the lungs to generate PMN128.