In study 1 (data set GSE139324 (9)), tumor-infiltrating leukocytes (TIL) from primary tumor tissue (n = 18) and CD45+ blood cells from immunotherapy-naïve HNSCC patients (18 HPV-, 8 HPV+), tonsil tissue from sleep apnea patients (n = 5), and CD45+ blood cells from healthy donors (n=6) were isolated. Here, PTPRC is linked to sleep apnea syndrome.