Telitacicept is a fully human TACI‐Fc fusion protein targeting B lymphocyte stimulator (BLyS) and a proliferating‐inducing ligand (APRIL) in late‐stage development for systemic lupus erythematosus, with a phase 3 trial in generalized MG ongoing (NCT05737160). The gene discussed is TNFRSF13B; the disease is systemic lupus erythematosus.