The PAQR3 genomic alteration in pan-cancer was analyzed by cBioPortal database (Fig. 5), and it was found that 1% of patients had PAQR3 genomic mutation, Amplification was the most dominant type of mutation in PAQR3, followed by Deep Deletion and Missense Mutation (Fig. 5a). The gene discussed is PAQR3; the disease is cancer.