FGF21 and obesity due to melanocortin 4 receptor deficiency: AAVMUSE could also be transduced into liver tissue to serve as a bio-factory to control the production of various therapeutic proteins based on controlling muscone dose and exposure time compared to traditional drugs that are static and cannot be adjusted, including thymic stromal lymphopoietin (TSLP)59 for treating obesity and FGF21 for treating diabetes60.