Genes associated with pentose phosphate (DERA, PGM2, NAMPT) and glycolysis (BPGM, LDHA, PFKFB3) revealed elevated expression in blood cells from active CAPS patients, and a decrease following anakinra treatment (Fig. 7D, Supplementary Fig. 7A). The gene discussed is DERA; the disease is cryopyrin-associated periodic syndrome.