Among others [25, 26], Molina and co-workers reported that 26% of Hispanics, 21% of Afro-Caribbeans, and 28% of African-American patients with SLE had at least one of the three aCL isotypes (IgG, IgM, IgA) [27]. The gene discussed is ACLY; the disease is systemic lupus erythematosus.