ADAMTS13 and Genetic thrombotic microangiopathy: In these cases, other causes of thrombotic microangiopathy should be excluded such as complement-mediated [atypical haemolytic uremic syndrome (aHUS)], ADAMTS13-mediated [thrombotic thrombocytemic purpura (TTP)], pregnancy-associated [haemolysis, elevated liver enzymes, and low platelet count (HELLP) syndrome], other autoimmune disorders-associated (systemic sclerosis), and infection- or drug-induced (immunosuppressives, chemotherapy, antibiotics) thrombotic microangiopathy [12, 142].