A potential mechanism could be possible anti-inflammatory properties of the MIND-diet.<h4>Objective</h4>To examine whether adherence to the MIND diet at baseline is associated with the odds of mild cognitive impairment (MCI) and changes in biomarkers of inflammation (High-sensitivity C-reactive Protein(hsCRP), interleukin-6(IL-6)) over three years in adults ≥70 years.<h4>Methods</h4>Adherence to the MIND diet was assessed by food frequency questionnaire (FFQ) at baseline and after three years. This evidence concerns the gene IL6 and Cognitive impairment.