Histological examination indicated a reduced occurrence of perivascularhemorrhages, and there were no indications of immune cell vascularsequestration in the ABCA1-deficient mice.13 Remarkably, a study discovered that variations in the human ABCA1promoter were linked to the severity of malaria,86 suggesting its key role in modulating the levels of pro-inflammatoryEVs during the disease. Here, ABCA1 is linked to malaria.