Among these populations, there were significant differences in expression of Classical_Neu and TXNIP/Gm2a_Neu between preoperative blood and NSCLC, while the proportion of Neu_c5_GSTP1(high)OASL(low), IL-7R + neutrophils, and IFIT1_Neu was significantly different between preoperative blood and para-carcinoma tissue (Fig. 2e). The gene discussed is TXNIP; the disease is non-small cell lung carcinoma.