Based on the previously established evaluation procedure, we found that several types of neutrophils were prevalent in the tissues and blood of lung cancer patients, namely Neu_c1_IL1B, Neu_c2_cxcr4(low), Neu_c3_CST7, IL-7R + neutrophils, Circulating neutrophils, Naïve neutrophils, IFN_experienced neutrophils, mNeu_14_ Lgals1, S100A12/Pabpc1_Neu, TXNIP/Gm2a_Neu, CD74_Neu and several general neutrophil groups (Fig. 2a-c, Table S5), whereas CD34_mNeu was expressed specifically in NSCLC. Here, S100A12 is linked to lung cancer.