We next examined plaque composition by focusing on two parameters commonly utilized as a surrogate indicators of atherosclerosis resolution: CD68+ area, a myeloid (macrophage) marker that represents plaque inflammation, and collagen area, a marker of plaque stability in humans (Libby and Aikawa, 2002; Soehnlein and Libby, 2021). Here, CD68 is linked to atherosclerosis.