RNF180 and gastric cancer: Several potential blood-based diagnostic methylation biomarkers have been identified for gastric cancer detection, including C13orf18, DLEC1, FLNC, HODX10, MGMT, PCDH10, RNF180, RPRM, RPRML, RUNX3, SEPT9, SFRP2, SOX17, THBS1, UCHL1, and ZNF56913,14 (Table 2).