Of note, HLA typing from PDX WES and RNA-Seq confirmed the LOH events affecting HLA-A, -B and -C genes identified in the corresponding patient tumors in two out of eight osteosarcoma (GR-OS-11 and GR-OS-17) and one out of four HGG PDXs (GR-HGG-4, GBM) (Figure 11; Supplementary Table S13). The gene discussed is HLA-A; the disease is osteosarcoma.