HLA-A and head and neck squamous cell carcinoma: A study of 15 adult cancers using an allele-specific machine learning algorithm reported a prevalence of HLA class I LOH ranging from 4 to 40% (in liver cancer and HNSCC, respectively), with 76% of LOH involving all three HLA-A, -B and -C genes, and 73% had a size > 1 Mb.