Multivariable MR analysis revealed that the hazard ratios of the probability of HCC were 3.045 (95%CI: 1.697-5.463, p = 2.77 × 10−4) for AST, 1.312 (95%CI: 0.713-2.414, p = 0.385) for ALT, 0.980 (95%CI: 0.0.779-1.232, p = 0.860) for ALP, and 1.296 (95%CI: 0.980-1.714, p = 0.072) for GGT (Table 3). Here, GPT is linked to hepatocellular carcinoma.