FGFR3 and hypochondroplasia: For instance, FGFR3: c.1138G>A (p.G380R) mutation accounted for 90% of the condition in achondroplasia patients (Bellus et al., 1995), while the FGFR3: c.1620C>A (p.N540K) mutation occurred in 70% of individuals with hypochondroplasia (Bellus et al., 2000).