As a result, researchers had explored several novel biomarkers for early detection of septic AKI, including kidney injury molecule-1 (KIM-1), neutrophil gelatinase-related lipocalin (NGAL), liver-type fatty acid binding protein (L-FABP), tissue inhibitor of metalloproteinase 2 (TIMP2), and insulin-like growth factor binding protein 7 (IGFBP7) (48–52). The gene discussed is IGFBP7; the disease is acute kidney injury.