GDF15 and Sepsis: Previous studies had identified several biomarkers such as oncostatin M (OSM), apoptosis inhibitor of the macrophage (AIM/CD5L), interleukin-26 (IL-26), interleukin-17D (IL-17D), interleukin-37 (IL-37), and growth differentiation factor-15 (GDF-15) as potential predictors of sepsis prognosis (6–11).