ADRB2 and amyotrophic lateral sclerosis: Because we have shown that catecholamines and β2-AR agonists induce anti-catabolic effects on skeletal muscle protein metabolism (Graça et al., 2013; Gonçalves et al., 2019) we next investigated the role of β2-AR activation in the expression of myokines and UPS- and ALS-related genes 3 h after a single bout of RE.