Both patterns also hold true for the comparison between glioblastoma and healthy controls, which lie closer in age to glioblastoma patients (8.674% more naive CD4+ T cells in healthy controls, 95% CI: 2.919 – 14.430, p = 0.003 and 0.439 times less mature NK cells in healthy controls, 95% CI: 0.277 – 0.696, p = 0.001). Here, CD4 is linked to glioblastoma.