Among them, TARBP1 was suggested to be involved in multiple cancers in human by regulating immune function (51); the significantly differential expression was observed in human Colorectal adenoma for the gene of KBTBD12 (52); it was reported that LTA4H can modulate the susceptibility to Mycobacterial infection in zebrafish and humans (53). This evidence concerns the gene KBTBD12 and colorectal adenoma.