Nonetheless, three genes (CNTNAP2, EHF, KDM4B; Fig. 6C; Additional file 8) were significantly upregulated by DHT in all four models of breast cancer and displayed enrichment of AR, GATA3, and H3K27ac ChIP-seq signals at associated genomic loci (Fig. 6D, E; Additional file 2: Fig. S7C). The gene discussed is GATA3; the disease is breast cancer.