SLPI and asthma: The increased proportion of Int Macro in the asthma model, characterized by down-regulation of genes related to neutrophil and granulocyte migration, chemotaxis, and inflammatory response (e.g., CCL9, CCL24, PF4) and upregulation of genes related activation of immune response and bacterial defense (e.g., IL1B and SLPI), suggested a potential protective role against inflammation.