To investigate the impact of NUDT5 on the growth of breast cancer cells, we employed siRNA-mediated knockdown in a panel of breast cell lines, including 3 ER-positive cell lines (MCF-7, ZR-75-1 and MDA-MB-361) and 3 TNBC cell lines (MDA-MB-231, MDA-MB-436 and MDA-MB-468). Here, NUDT5 is linked to breast cancer.