GSEA of the differentially expressed genes between PARD3 wild-type and overexpressing cancer cells showed enrichment of these genes in gene sets related to cell motility, cell adhesion and epithelial-to-mesenchymal transition (EMT) in PARD3-overexpressing cells (Fig. 3F), further indicating that EMT and stemness are positively correlated in cancer. This evidence concerns the gene PARD3 and cancer.