The expression levels of three writers (DNMT1, DNMT3A, DNMT3B), two erasers (TET1, TET3), and eight readers (MBD4, ZBTB33, UHRF1, UHRF2, UNG, TDG, NTHL1, SMUG1) were dramatically higher in tumor tissues (p < 0.05). This evidence concerns the gene DNMT3A and neoplasm.