TWIST1 and renal cell carcinoma: To investigate the molecular mechanism of sunitinib resistance and Twist overexpression on the Wnt/β-catenin pathway and EMT in renal cell carcinoma, we performed Western blot analysis to identify the differentially expressed proteins among SR-A498 cells, oe-Twist A498 cells, oe-Twist SR-A498 cells, and control cells.