STXBP1 and Intellectual disability: De novo pathogenic mutations of the STXBP1 gene lead to developmental epileptic encephalopathies (DEE)—a set of neurodevelopmental conditions associated with intellectual disability (STXBP1-DEE) (Abramov et al, 2021; Chen et al, 2020; Guiberson et al, 2018; Miyamoto et al, 2017).