In addition, in ncCL and GC2 we were able to detect the induction of IFI27, an interferon-inducible gene, (Fig. 7D) similar as reported for whole blood samples from SLE patients (Becker et al, 2013; Ishii et al, 2005; Wang et al, 2022c) and as observed by the induction of IFNSG in our bulk RNA sequencing data (Fig. 2C). This evidence concerns the gene IFI27 and systemic lupus erythematosus.