A candidate marker analysis performed using COMET19, revealed that CD36 is ranked as a candidate marker for isolation of cluster C1 as CD36+ (Supplementary Fig. 6c), therefore we propose that CD36 can be used as a candidate marker to isolate CD45.1+ CD11b+ F4/80+ CD36− macrophages as those functionally altered by the CML niche. The gene discussed is CD36; the disease is chronic myelogenous leukemia, BCR-ABL1 positive.