CML-exposed subpopulations C2 and C6 also display a gene signature with high expression of immature macrophage genes such as Ly6c2 and an anti-inflammatory signature including enrichment for Tgfbi and Lgals1 (Fig. 3d; Supplementary Fig. 6a). The gene discussed is TGFBI; the disease is chronic myelogenous leukemia, BCR-ABL1 positive.