As a matter of fact, radiation-induced IL-1 is highly relevant to radiation-induced pneumonitis and skin fibrosis (Müller & Meineke, 2007), which are the results of stimulation of proliferation of keratinocytes and fibroblasts and the induction of matrix metalloproteases and collagen synthesis (Chen et al, 2005; Lierova et al, 2018). The gene discussed is IL1B; the disease is pneumonitis.