There are many risk factors that lead to IL-4 over-exposure in the neonatal phase and childhood, including allergic asthma, allergies to foods such as milk and eggs, bronchiolitis, and measles virus infection in the early stage (Han et al. 2016; Hammad and Lambrecht 2015; Sicherer et al. 2010; Smith et al. 2019). Here, IL4 is linked to allergic asthma.