Koh et al. recently showed that molecular classification of SCLCs can be applied to extrapulmonary neuroendocrine carcinomas/poorly differentiated carcinomas (EP-NEC/PDCs) and that POU2F3-dominant or YAP1-dominant subtypes are distinct subtypes of EP-NEC/PDCs [75]. Here, YAP1 is linked to neuroendocrine carcinoma.