Nuclear protein in testis (NUT) carcinomas (NCs) are rare, clinically aggressive carcinomas that are characterized by a translocation involving the NUTM1 gene on chromosome 15q14 and, in most cases (~ 70–80%), the bromodomain-containing 4 (BRD4) gene on chromosome 19p13.1, resulting in a BRD4-NUTM1 fusion oncogene [4, 5]. The gene discussed is NUTM1; the disease is nut midline carcinoma.