SP7 and osteogenesis imperfecta: Mouse models for osteogenesis imperfecta are good examples, including the collagen 1 α1 chain G610C mutation (Col1a1G610C) model, or the less common mutations in interferon induced transmembrane protein 5 (Ifitm5), osterix (Sp7), and Wingless-related integration site 1 (Wnt1) described below.