When comparing small cell lung tissues with paired normal lung tissues from different patients, several tumor metastasis and tumor microenvironment regulators, such as caveolin-1, platelets, endothelial cell adhesion molecule 1, and stathmin 1 (STMN1), are modified by Kcr, underlying the broad spectrum of functions of Kcr-modified proteins in small cell lung cancer (SCLC). Here, CAV1 is linked to small cell lung carcinoma.