HDAC2 and head and neck squamous cell carcinoma: Based on Kcr regulators, a nine-gene signature, including DPF2, HDAC2, and HDAC3, was established and validated as an independent factor for prognosis in patients with HNSCC; this could effectively distinguish patients into low- and high-risk groups depending on the difference in OS using the GEO-HNSCC dataset (p = 0.023) [126].